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Disease guide

Symptoms, causes, treatments.

Plain-language reference for the most common freshwater, brackish, and saltwater aquarium diseases. Drawn from established hobbyist literature — not a substitute for an aquatic veterinarian when a condition is severe or doesn’t respond to treatment.

Parasitic

Ich

Serious
Ichthyophthirius multifiliis

Pinhead-sized white spots scattered across the body, fins, and gills — like the fish has been dusted with salt. Fish flash against decor (scratch sides of body), clamp fins, breathe rapidly, and lose appetite as the parasite multiplies. Gill infestations can suffocate before spots are visible on the body.

FreshwaterContagious

Camallanus Worms

Serious
Camallanus cotti

Thin red worms (1-3 mm) protruding from the anus, often visible only intermittently as they retract. The worms anchor in the intestinal wall. Fish becomes thin despite eating, develops a bloated abdomen, loses color, and produces white stringy feces. Late-stage cases stop eating. Most common in livebearers (guppies, mollies, platies), Discus, and Apistogramma.

FreshwaterContagious

Hexamita / Hole-in-the-Head

Serious
Hexamita salmonis

Pitted lesions on the head, particularly above the eyes and along the lateral line — start as small pinpricks and erode into deeper craters that may leak pale stringy mucus. White, stringy feces. Loss of appetite and weight loss despite the fish appearing to feed. Color fading. Most pronounced in Discus, Oscars, Severums, large cichlids, marine angels, and tangs.

FreshwaterSaltwaterContagious

Marine Ich

Critical
Cryptocaryon irritans

Tiny white spots on the body and fins — slightly larger and rounder than freshwater Ich. Heavy infestations show breathing distress as gills are colonized. Flashing against rock and substrate. Discolored patches, ragged fins. Most virulent on tangs, angels, butterflies — but no marine fish is immune. Mortality is high if untreated.

SaltwaterContagious

Marine Velvet

Critical
Amyloodinium ocellatum

Fine gold or dusty sheen across the body — like the fish has been sprinkled with powdered sugar. Often easier to see under a flashlight in a dim tank. Rapid gilling, scratching, color loss. Velvet kills FAST — fish can die within 24-48 hours of symptoms appearing, often before the gold dust is widely visible. Sudden mass mortality without obvious cause is often Velvet, especially in clownfish.

SaltwaterContagious

Brooklynella

Critical
Brooklynella hostilis

Excess mucus production — fish develops a cloudy, peeling, gray-white slime coat that sloughs off in sheets. Rapid breathing, gasping at the surface, lethargy, refusing food. Often presents first in newly-imported clownfish, especially wild-caught Maroons and Tomatoes. Mortality is high and fast — 24-48 hours from first symptoms is common.

SaltwaterContagious

Bacterial

Environmental

Symptom complex

This is general hobbyist reference, not veterinary advice. Diagnosing a sick fish from symptoms alone is uncertain — many conditions look identical at the surface. For valuable specimens or anything that doesn’t respond to a standard course of treatment, consult an aquatic veterinarian. The American Association of Fish Veterinarians (AAFV) maintains a public directory.
12 entries · Drawn from hobbyist literature · Verify with a vet for valuable specimens